Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.69 |
| ▸ | CTSK | P43235 | 12/20 | 0.66 |
| ▸ | CTSL | P07711 | 4/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.59 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29308017 | 0.93 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL2471949 | 0.93 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8823914 | 0.93 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL9338295 | 0.93 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8584264 | 0.91 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL7313791 | 0.90 | CAPN1 (0.64) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8583015 | 0.90 | CTSK (0.66) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8584325 | 0.89 | CAPN1 (0.70) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8586283 | 0.89 | CAPN1 (0.70) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8585289 | 0.89 | CAPN1 (0.69) | CAPN1CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840614-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1996041638-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | WO | claimed |
| EP-0840614-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996041638-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | WO | disclosed |