Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.78 |
| ▸ | CTSK | P43235 | 11/20 | 0.75 |
| ▸ | CTSL | P07711 | 5/20 | 0.70 |
| ▸ | CTSS | P25774 | 3/20 | 0.70 |
| ▸ | CTSB | P07858 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823914 | 1.00 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL9338295 | 1.00 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL2471949 | 1.00 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8584264 | 0.95 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8585293 | 0.95 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8585289 | 0.93 | CAPN1 (0.69) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8584262 | 0.93 | CAPN1 (0.69) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL7612532 | 0.91 | CTSK (0.71) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL7612544 | 0.91 | CTSK (0.71) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL8823936 | 0.91 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366779-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | SEAGEN INC (US) | 2024-11-07 | — | — | US | disclosed |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240207427-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | SEAGEN INC (US) | 2024-06-27 | — | — | US | disclosed |
| EP-4308170-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | Seagen Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4308171-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | Seagen Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117120097-A | Selective drug release of internalized bioactive compound conjugates | 思进公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230091653-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | SEAGEN INC. | 2023-03-23 | — | — | US | disclosed |
| WO-2022198231-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | SEAGEN INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022198232-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | SEAGEN INC. (US) | 2022-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207427-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | CTSB, CTSE, CTSZ | CAPN1 232/4885CTSK 11/4885CTSL 14/4885 |
| US-20240366779-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | CTSB, CTSE, CTSZ | CAPN1 232/4885CTSK 11/4885CTSL 14/4885 |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | CTSB, CTSE, CTSZ | CAPN1 232/4885CTSK 11/4885CTSL 14/4885 |
| US-20230091653-A1 | SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS | CTSB, CTSE, CTSZ | CAPN1 232/4885CTSK 11/4885CTSL 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.