Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014512 | 0.80 | SLC18A3 (0.51) | SLC18A3ALDH1A1LMNA | |
| SCHEMBL7013419 | 0.76 | GSK3B (0.42) | LMNA | |
| SCHEMBL27986060 | 0.75 | TMEM97 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL3277741 | 0.75 | SIGMAR1 (0.54) | ALDH1A1 | |
| SCHEMBL3272922 | 0.75 | SIGMAR1 (0.54) | ALDH1A1 | |
| SCHEMBL3272931 | 0.75 | SIGMAR1 (0.54) | ALDH1A1 | |
| SCHEMBL10864984 | 0.73 | GRIN2B (0.36) | — | |
| SCHEMBL20449122 | 0.72 | KDM1A (0.43) | KDM4EALDH1A1 | |
| SCHEMBL20449121 | 0.72 | KDM1A (0.43) | KDM4EALDH1A1 | |
| SCHEMBL7221409 | 0.72 | DRD1 (0.45) | MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808069-A | Salts of 2-(3-benzoylphenyl) propionic acid with organic bases and pharmaceutical compositions thereof | DOMPE' FARMACEUTICI SPA (IT) | 1998-09-15 | — | — | US | claimed |
| EP-0703893-A1 | SALTS OF 2-(3-BENZOYLPHENYL) PROPIONIC ACID WITH ACHIRAL AND CHIRAL ORGANIC BASES AND PHARMACEUTICAL COMPOSITIONS THEREOF | DOMPE FARMACEUTICI S.P.A. (IT) | 1996-04-03 | — | — | EP | claimed |
| WO-1994020449-A1 | SALTS OF 2-(3-BENZOYLPHENYL)PROPIONIC ACID WITH ACHIRAL AND CHIRAL ORGANIC BASES AND PHARMACEUTICAL COMPOSITIONS THEREOF | DOMPE'FARMACEUTICI SPA (IT) | 1994-09-15 | — | — | WO | claimed |