SCHEMBL858472

SCHEMBL858472

CCC(C)c1ccc(OP)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
GAA P10253 2/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 2/20 0.39
USP2 O75604 1/20 0.39
PKM P14618 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
ALOX12 P18054 1/20 0.39
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16683084 0.83 ALDH1A1 (0.46) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL7951316 0.80 ALDH1A1 (0.36) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL12697240 0.80 ALDH1A1 (0.43) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL7951319 0.78 ALDH1A1 (0.38) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL27456625 0.77 ALDH1A1 (0.37) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL7951325 0.76 ALDH1A1 (0.36) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL4456300 0.75 ALDH1A1 (0.42) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL875855 0.75 ALDH1A1 (0.59) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL8298141 0.73 ALDH1A1 (0.60) ALDH1A1GAAHPGDALOX15USP2
SCHEMBL10182749 0.73 ALDH1A1 (0.43) ALDH1A1GAAHPGDALOX15USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143324-B2 antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-27 US disclosed
US-20090275673-A1 Benzocyclobutene based polymer formulations and methods for processing such formulations in oxidative environments DOW GLOBAL TECHNOLOGIES LLC 2009-11-05 US disclosed