Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581845 | 0.90 | TBXAS1 (0.59) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8583156 | 0.86 | TBXAS1 (0.64) | TBXAS1PTGDR2 | |
| SCHEMBL8578689 | 0.83 | HPGD (0.44) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8584111 | 0.81 | LMNA (0.46) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8585291 | 0.80 | TBXAS1 (0.48) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8539577 | 0.79 | TBXAS1 (0.61) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8581374 | 0.77 | TBXAS1 (0.48) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8581839 | 0.74 | TBXAS1 (0.46) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL11036475 | 0.74 | TBXAS1 (0.63) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8539634 | 0.73 | TBXAS1 (0.60) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |