SCHEMBL8585697

SCHEMBL8585697

CC(=O)c1ccccc1F.O=C(CCl)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
PTPN1 P18031 1/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
ALOX15 P16050 1/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 4/20 0.44
MEN1 O00255 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CTNNB1 P35222 2/20 0.44
WNT3A P56704 2/20 0.44
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
GSK3B P49841 2/20 0.42
TRPA1 O75762 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779889 0.91 ALDH1A1 (0.59) ALDH1A1PTPN1ERCC5FEN1ALOX15
SCHEMBL1427156 0.91 ALDH1A1 (0.59) ALDH1A1PTPN1ERCC5FEN1ALOX15
SCHEMBL29593208 0.84 CES2 (0.65) ALDH1A1PTPN1ERCC5FEN1ALOX15
SCHEMBL13461 0.84 CES2 (0.65) ALDH1A1PTPN1ERCC5FEN1ALOX15
Hydrochloric Acid SCHEMBL7418290 0.82 CES2 (0.62) ALDH1A1PTPN1ERCC5FEN1ALOX15
SCHEMBL29169247 0.79 CES2 (0.58) ALDH1A1PTPN1ERCC5FEN1ALOX15
Fluorobenzene SCHEMBL28799844 0.77 CES2 (0.56) ALDH1A1PTPN1ERCC5FEN1ALOX15
Isopropyl Alcohol SCHEMBL29078917 0.77 CES2 (0.56) ALDH1A1PTPN1ERCC5FEN1ALOX15
SCHEMBL11737575 0.76 ALDH1A1 (0.61) ALDH1A1ERCC5FEN1ALOX15CES2
SCHEMBL8585700 0.76 PTPN1 (0.44) ALDH1A1PTPN1ERCC5FEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998035560-A1 HERBICIDAL COMPOSITION FOR USE IN RICE CROP E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-08-20 WO disclosed