⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26118223 | 0.98 | — | — | |
| Methylene Chloride SCHEMBL28269018 | 0.94 | ALDH1A1 (0.62) | — | |
| SCHEMBL259480 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL14685862 | 0.80 | ALDH1A1 (0.62) | — | |
| Bromide SCHEMBL3960541 | 0.80 | ALDH1A1 (0.62) | — | |
| Water SCHEMBL27839644 | 0.80 | ALDH1A1 (0.62) | — | |
| Bromide SCHEMBL6298964 | 0.80 | ALDH1A1 (0.62) | — | |
| Bromide SCHEMBL6298962 | 0.80 | ALDH1A1 (0.62) | — | |
| SCHEMBL290725 | 0.78 | — | — | |
| SCHEMBL13066854 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180891-A1 | SYNERGISTIC MODULATORS OF ALPHA-DICARBONYL DETOXIFICATION AND THEIR USE FOR INDUCING WEIGHT LOSS AND THE TREATMENT OF DIABETIC PATHOLOGIES | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2024-06-06 | — | — | US | claimed |
| CN-115925649-A | Method for preparing 4-methylthiazole-5-formaldehyde by continuous flow | 深圳市茵诺圣生物科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| WO-2022140279-A1 | SYNERGISTIC MODULATORS OF ALPHA-DICARBONYL DETOXIFICATION AND THEIR USE FOR INDUCING WEIGHT LOSS AND THE TREATMENT OF DIABETIC PATHOLOGIES | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2022-06-30 | — | — | WO | claimed |
| CN-112778231-A | Novel synthesis method of 4-methylthiazole-5-formaldehyde | 杭州凯方科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-109180704-B | Synthesis method of cefditoren pivoxil | 齐鲁安替制药有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-109180704-A | A kind of synthetic method of Cefditoren pivoxil Cephalosporins | 齐鲁安替制药有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-100360511-C | Method for synthesizing 4-methyl-5-methyol thiazole | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-1803782-A | Method for synthesizing 4-methyl-5-methyol thiazole | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-07-19 | — | — | CN | claimed |
| WO-2005100330-A1 | PREPARATION OF INTERMEDIATE FOR 3-[2-(4-METHYLTHIAZOLE-5-YL)VINYL] CEPHALOSPORINS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| CN-1628108-A | Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate | ORCHID CHEMICALS & PHARM LTD (IN) | 2005-06-15 | — | — | CN | claimed |
| US-6833459-B2 | Reducing thiazole ester to thiazole alcohol using sodium borohydride in the presence of aluminum chloride in a solvent and oxidising the thiazole alcohol to obtain 4-methyl-5-formyl-thiazole | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-12-21 | — | — | US | claimed |
| WO-2003091230-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-11-06 | — | — | WO | claimed |
| US-20030204095-A1 | Process for the preparation of thiazole intermediate | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-10-30 | — | — | US | claimed |
| US-20260070896-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2026-03-12 | — | — | US | disclosed |
| WO-2026041663-A1 | P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2026-02-26 | — | — | WO | disclosed |
| US-20250376461-A1 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2025-12-11 | — | — | US | disclosed |
| US-4732977-A | BACTERICIDES | BRISTOL MYERS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0040696-B1 | AMINOTHIADIAZOLES AS GASTRIC SECRETION INHIBITORS | MERCK & CO. INC. (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0040696-A2 | Aminothiadiazoles as gastric secretion inhibitors | MERCK & CO. INC. (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4200578-A | ANTIULCER AGENTS, BLOCKING AGENTS, ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-04-29 | — | — | US | disclosed |