Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847991 | 0.84 | MAPT (0.70) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL638831 | 0.82 | TP53 (0.62) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL1198848 | 0.81 | TP53 (0.61) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL1198598 | 0.79 | TP53 (0.59) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL31602906 | 0.78 | NPC1 (0.56) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6555297 | 0.78 | NPC1 (0.56) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5550221 | 0.78 | HTT (0.62) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL14998701 | 0.77 | TP53 (0.57) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL5583502 | 0.76 | MAPK1 (0.57) | TP53MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL5583501 | 0.76 | TP53 (0.56) | TP53MAPTMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814833-A | OPTICAL AND ELECTRONIC POLYMERS FOR ELECTRONICS, PHOTONICS AND OPTOELECTRONICS APPLICATIONS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-09-29 | — | — | US | disclosed |
| US-5597890-A | ENHANCED LUMINESCENCE AND PHOTOGENERATION OF CHARGE CARRIERS AND QUANTUM EFFICIENCY USING N-HETEROCYCLE AROMATIC RESINS AND AN ELECTRON DONOR OR ACCEPTOR; OPTOELECTRONICS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1994004592-A1 | PHOTOCONDUCTIVE POLYMERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |