Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584509 | 0.82 | NOX1 (0.40) | NOX1 | |
| SCHEMBL8582555 | 0.80 | ADRA2A (0.38) | NOX1 | |
| SCHEMBL16974909 | 0.80 | NOX1 (0.38) | NOX1 | |
| SCHEMBL8585872 | 0.78 | NOX1 (0.44) | NOX1 | |
| SCHEMBL8662194 | 0.77 | ABL1 (0.38) | NOX1HTR2A | |
| SCHEMBL8586573 | 0.77 | NOX1 (0.36) | NOX1LMNA | |
| SCHEMBL7069919 | 0.77 | CA12 (0.38) | L3MBTL1 | |
| SCHEMBL8583208 | 0.76 | NOX1 (0.37) | NOX1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL8580850 | 0.74 | HTR2A (0.39) | NOX1HTR2ALMNAKMT2A | |
| SCHEMBL16974874 | 0.74 | NOX1 (0.37) | NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906297-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997049692-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-12-31 | — | — | WO | disclosed |