Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974836 | 0.85 | IL1B (0.32) | NOX1 | |
| SCHEMBL8584509 | 0.83 | NOX1 (0.40) | NOX1 | |
| SCHEMBL8582555 | 0.81 | ADRA2A (0.38) | NOX1 | |
| SCHEMBL8586554 | 0.80 | NOX1 (0.37) | NOX1 | |
| SCHEMBL8585872 | 0.79 | NOX1 (0.44) | NOX1 | |
| SCHEMBL8662194 | 0.78 | ABL1 (0.38) | NOX1 | |
| SCHEMBL8586573 | 0.78 | NOX1 (0.36) | NOX1 | |
| SCHEMBL8720094 | 0.78 | L3MBTL1 (0.38) | — | |
| SCHEMBL8582531 | 0.77 | NOX1 (0.37) | NOX1 | |
| SCHEMBL8580850 | 0.76 | HTR2A (0.39) | NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099304-A1 | NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA | Mayo Foundation for Medical Education and Research (US) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015117024-A1 | NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2015-08-06 | — | — | WO | disclosed |