Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587646 | 0.98 | KDM4E (0.57) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL837139 | 0.93 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL23163730 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTCYP3A4CYP2C19HPGD | |
| SCHEMBL16287573 | 0.85 | KCNA3 (0.48) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL8584110 | 0.85 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL3485457 | 0.84 | MAPT (0.54) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL503291 | 0.84 | KMT2A (0.65) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL13692378 | 0.84 | CYP3A4 (0.58) | KDM4EALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL23163646 | 0.84 | HRH3 (0.47) | KDM4EALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL25460831 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1MAPTMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117210834-A | Electrochemical-based promotion of CO 2 Method for synthesizing dicarboxylic acid compound | 四川大学 | 2023-12-12 | — | — | CN | disclosed |
| US-20210171520-A1 | EP300/CREBBP INHIBITOR | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-10 | — | — | US | disclosed |
| WO-1998031697-A1 | ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF | SANKYO COMPANY, LIMITED (JP) | 1998-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171520-A1 | EP300/CREBBP INHIBITOR | EP300, CREBBP, CREB1 | KDM4E 278/4885ALDH1A1 1619/4885MAPT 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.