Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393191 | 0.79 | CTSK (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1774458 | 0.78 | CTSK (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14753873 | 0.77 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15218741 | 0.77 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3483388 | 0.77 | RIPK1 (0.38) | — | |
| SCHEMBL12393194 | 0.75 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12393190 | 0.75 | CTSK (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7864386 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8434418 | 0.73 | MAPT (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8366044 | 0.73 | CTSK (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998039349-A1 | PROTECTING GROUP FOR SYNTHESIZING OLIGONUCLEOTIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |