Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590569 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL8589940 | 0.86 | ALDH1A1 (0.56) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL8540467 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL8616384 | 0.77 | CHRNB2 (0.40) | ALDH1A1 | |
| SCHEMBL8538897 | 0.75 | ALDH1A1 (0.66) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL8590205 | 0.75 | TMEM97 (0.46) | HRH3OPRK1OPRM1OPRD1 | |
| SCHEMBL8590054 | 0.74 | HCRTR2 (0.40) | KDM4ETSHRNPSR1KMT2A | |
| SCHEMBL22201130 | 0.74 | CHRNB2 (0.53) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL2172790 | 0.74 | CHRNB2 (0.53) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL28508997 | 0.73 | ALDH1A1 (0.72) | KDM4EALDH1A1GAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |