SCHEMBL8587141

SCHEMBL8587141

CC(C)C(C=O)NC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PAX8 Q06710 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24581089 0.84 NPC1 (0.33) NPC1ALDH1A1PAX8
SCHEMBL1657294 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL3281621 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL1120061 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL9484445 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL13049385 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL5464777 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL1031751 0.77 PAX8 (0.47) PAX8
SCHEMBL1035825 0.76 DPP4 (0.52) PAX8
SCHEMBL1036136 0.76 CTSC (0.35) PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10001381-A None JP disclosed
US-20240116832-A1 INHIBITORS OF SOIL NITRIFICATION AND PROCESSES TO PREVENT SAME TESSENDERLO GROUP NV (BE) 2024-04-11 US disclosed
WO-2021076458-A9 INHIBITORS OF SOIL NITRIFICATION AND PROCESSES TO PREVENT SAME TESSENDERLO GROUP NV (BE) 2021-07-15 WO disclosed
JP-H101381-A PRODUCTION OF GRANULAR FERTILIZER DENKI KAGAKU KOGYO KK 1998-01-06 JP disclosed