Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL3690345 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Ethylene SCHEMBL28823818 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Ethylene SCHEMBL28596290 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL5068661 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL34 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| P-Xylene SCHEMBL8660591 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL1705904 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL31313 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL11432043 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL29991938 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322400-A | Light-color kenaf lignin nano spherical particles and preparation method and application thereof | 齐鲁工业大学 | 2022-11-11 | — | — | CN | claimed |
| CN-106220031-A | A kind of anti-crack concrete water reducer and preparation method thereof | 合肥永佳新材料科技有限公司 | 2016-12-14 | — | — | CN | claimed |
| JP-10251573-A | — | — | None | — | — | JP | disclosed |
| CN-116987284-A | Preparation method and application of light-colored nano granular lignin | 齐鲁工业大学(山东省科学院) | 2023-11-03 | — | — | CN | disclosed |
| CN-115715194-A | Methods of treating coronavirus disease 2019 | 辉瑞公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115322400-A | Light-color kenaf lignin nano spherical particles and preparation method and application thereof | 齐鲁工业大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113621130-A | Preparation method of high-quality spinning asphalt, product and application thereof | 武汉科技大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-106220031-A | A kind of anti-crack concrete water reducer and preparation method thereof | 合肥永佳新材料科技有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-106220031-A | A kind of anti-crack concrete water reducer and preparation method thereof | 合肥永佳新材料科技有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-101250105-B | Method for synthesizing bio-diesel by using p-toluenesulfonic acid formaldehyde condensation polymer | UNIV EAST CHINA NORMAL | 2010-06-09 | — | — | CN | disclosed |
| CN-101250105-A | Method for synthesizing bio-diesel by using p-toluenesulfonic acid formaldehyde condensation polymer | UNIV EAST CHINA NORMAL (CN) | 2008-08-27 | — | — | CN | disclosed |
| JP-H10251573-A | INK COMPOSITION FOR JET PRINTING | DAINIPPON TORYO CO LTD | 1998-09-22 | — | — | JP | disclosed |
| US-4341301-A | Adhesive securing of anchors in borehole | BERGWERKSVERBAND GMBH (DE) | 1982-07-27 | — | — | US | disclosed |