Tyrosine

Tyrosine

SCHEMBL8587284

C[C@H](Nc1ccccc1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.67
PTGS1 P23219 2/20 0.57
ALPI P09923 1/20 0.57
PKM P14618 1/20 0.57
XIAP P98170 1/20 0.57
OPRD1 P41143 7/20 0.48
OPRM1 P35372 4/20 0.48
OPRK1 P41145 1/20 0.48
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
ALOX15 P16050 1/20 0.47
HTR2A P28223 1/20 0.47
PTGS2 P35354 1/20 0.47
RECQL P46063 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL28362061 1.00 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL28377241 0.88 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL2284689 0.84 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28019917 0.84 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28049225 0.84 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1908049 0.83 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5699043 0.83 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1908048 0.83 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28900255 0.83 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL133206 0.83 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759543-A TREATMENT OF OBESITY, LEUCOPENIA AND AUTOIMMUNE ANTIBODIES CAUSED BY INFECTIONS OR ANTIGENS KRESTYANSKOE KHOZYAISTVO "AGROFIRMADIZHA" (RU) 1998-06-02 US disclosed