Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16125688 | 0.83 | ADORA2A (0.45) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| SCHEMBL8587151 | 0.83 | ADORA3 (0.35) | ADORA2AADORA3ADORA1ADORA2BHSP90B1 | |
| SCHEMBL31293603 | 0.79 | ADORA3 (0.47) | ADORA3HINT1 | |
| SCHEMBL3622556 | 0.79 | ADORA2A (0.59) | ADORA2AADORA3ADORA1ADORA2BADA | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12939406 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL15628197 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14762374 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14816756 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL19493379 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B | |
| Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12219172 | 0.78 | ADORA2A (0.66) | ADORA2ACYP2C19ADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001456-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-02-06 | — | — | WO | claimed |
| WO-1998042352-A1 | METHOD FOR TREATING B-CELL TUMORS WITH ARA-G NUCLEOSIDE DERIVATIVES | GLAXO GROUP LTD. (GB) | 1998-10-01 | — | — | WO | disclosed |
| WO-1992001456-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-02-06 | — | — | WO | disclosed |