Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276911 | 0.80 | MAPT (0.44) | MAPTALDH1A1L3MBTL1NPSR1MEN1 | |
| SCHEMBL9613243 | 0.77 | MAPT (0.50) | MAPTALDH1A1L3MBTL1NPSR1MEN1 | |
| SCHEMBL12557597 | 0.73 | ALDH1A1 (0.38) | MAPTALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL12905301 | 0.71 | MAPT (0.45) | MAPTALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL8611180 | 0.71 | ALDH1A1 (0.36) | MAPTALDH1A1L3MBTL1NPSR1MEN1 | |
| SCHEMBL15166977 | 0.71 | MAPT (0.38) | MAPTALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL21803044 | 0.70 | MEN1 (0.38) | MAPTALDH1A1NPSR1KDM4EPOLB | |
| SCHEMBL7090808 | 0.70 | NPSR1 (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11642453 | 0.69 | MAPT (0.31) | MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL11643739 | 0.69 | MAPT (0.31) | MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998030535-A1 | AMINO ACID COMPOUNDS | COCKBAIN JULIAN (GB) | 1998-07-16 | — | — | WO | disclosed |