Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | CASP2 | P42575 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085489 | 0.92 | PAOX (0.53) | PAOXCA12CA2CA4CA6 | |
| SCHEMBL18507254 | 0.89 | PAOX (0.50) | PAOXCA12CA2CA4CA6 | |
| SCHEMBL23929060 | 0.89 | PAOX (0.50) | PAOXCA12CA2CA4CA6 | |
| SCHEMBL6745342 | 0.89 | TSHR (0.54) | PAOXCA2CASP2MEN1KMT2A | |
| SCHEMBL6745339 | 0.89 | TSHR (0.54) | PAOXCA2CASP2MEN1KMT2A | |
| SCHEMBL24761185 | 0.89 | SLC6A5 (0.51) | PAOXCA2CASP2CYP1A2MEN1 | |
| SCHEMBL5357869 | 0.88 | PAOX (0.59) | PAOXCA12CA2CA4CA6 | |
| SCHEMBL14360491 | 0.88 | PAOX (0.53) | PAOXCA12CA2CA4CA6 | |
| SCHEMBL9506604 | 0.86 | SLC6A5 (0.59) | PAOXALOX15MEN1RECQLKMT2A | |
| SCHEMBL27176325 | 0.86 | SLC6A5 (0.49) | PAOXCASP2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050418-A1 | CATIONIC AMPHIPHILES CONTAINING LINKERS DERIVED FROM NEUTRAL OR POSITIVELY CHARGED AMINO ACIDS | GENZYME CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |