Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745339 | 1.00 | TSHR (0.54) | TSHRSLC6A5PAOXCASP2FAAH | |
| SCHEMBL24761185 | 0.95 | SLC6A5 (0.51) | TSHRSLC6A5PAOXCASP2FAAH | |
| SCHEMBL9506604 | 0.93 | SLC6A5 (0.59) | TSHRSLC6A5PAOXFAAHKDM4A | |
| SCHEMBL27176325 | 0.92 | SLC6A5 (0.49) | TSHRSLC6A5PAOXCASP2KDM4A | |
| SCHEMBL20753032 | 0.91 | LMNA (0.56) | TSHRSLC6A5MAPTMEN1KMT2A | |
| SCHEMBL5493471 | 0.90 | SLC6A5 (0.47) | TSHRSLC6A5PAOXCASP2KDM4A | |
| SCHEMBL8587740 | 0.89 | PAOX (0.52) | TSHRSLC6A5PAOXCASP2CA1 | |
| SCHEMBL10594732 | 0.89 | SLC6A5 (0.47) | TSHRSLC6A5PAOXCASP2FAAH | |
| SCHEMBL27909370 | 0.89 | SLC6A5 (0.51) | TSHRSLC6A5PAOXCASP2FAAH | |
| SCHEMBL17379929 | 0.88 | SLC6A5 (0.64) | TSHRSLC6A5PAOXCASP2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |