SCHEMBL8588060

SCHEMBL8588060

Cc1ccccc1C(=O)C(O)[C@H]1OC(Cl)[C@@H](O)[C@@]1(O)C(=O)c1ccccc1C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HTT P42858 1/20 0.31
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707655 0.81 NPC1 (0.32) SLC6A2SLC6A4SLC6A3HTT
SCHEMBL3392385 0.80 HTT (0.31) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL30751007 0.78 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL8960840 0.77 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL6842407 0.77 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL2907033 0.77 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL5707587 0.77 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3HTTPIK3CD
SCHEMBL5707579 0.77 NPC1 (0.31)
SCHEMBL5707724 0.77 NPC1 (0.31)
Hydrochloric Acid SCHEMBL29878392 0.77 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3HTTPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998039347-A2 SYNTHESIS OF L-RIBOSE AND 2-DEOXY L-RIBOSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-09-11 WO disclosed