Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707587 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL2907033 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL6842407 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL3395341 | 0.87 | HTT (0.33) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL4750928 | 0.85 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL4982728 | 0.84 | P2RX7 (0.32) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL5707632 | 0.84 | P2RX7 (0.32) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL5707571 | 0.84 | P2RX7 (0.32) | SLC6A2SLC6A4SLC6A3P2RX7HTT | |
| SCHEMBL4411815 | 0.79 | CTNNB1 (0.32) | P2RX7HTTCTNNB1WNT3AALDH1A1 | |
| SCHEMBL4986617 | 0.79 | NPC1 (0.33) | SLC6A2SLC6A4SLC6A3P2RX7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525711-A | MONOMERS FOR DNA AMPLIFICATION PROCEDURES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-11 | — | — | US | disclosed |