SCHEMBL5707724

SCHEMBL5707724

CO[C@H]1O[C@@H](C(O)C(=O)c2ccccc2C)[C@@](O)(C(=O)c2ccccc2C)[C@H]1Br

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707579 1.00 NPC1 (0.31) NPC1RAB9AALDH1A1KMT2A
SCHEMBL5707655 0.86 NPC1 (0.32) NPC1RAB9A
SCHEMBL5707590 0.78 NPC1 (0.33) NPC1RAB9AALDH1A1KMT2A
SCHEMBL8588060 0.77 SLC6A2 (0.31)
SCHEMBL5707591 0.77 NPC1 (0.32) NPC1RAB9A
SCHEMBL5707623 0.76 NPC1 (0.31) NPC1RAB9AALDH1A1
SCHEMBL5707551 0.75 NPC1 (0.32) NPC1RAB9AALDH1A1
SCHEMBL4982728 0.74 P2RX7 (0.32) NPC1RAB9AALDH1A1KMT2A
SCHEMBL5707571 0.74 P2RX7 (0.32) NPC1RAB9AALDH1A1KMT2A
SCHEMBL5707632 0.74 P2RX7 (0.32) NPC1RAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO. INC (JP) 2006-10-12 US disclosed
EP-1705181-A2 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO., INC. (JP) 2006-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound DCTD, DERA, HDHD5 NPC1 2614/4885RAB9A 2001/4885ALDH1A1 637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.