Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019098 | 0.82 | CHRM1 (0.54) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL28740155 | 0.82 | CHRM2 (0.39) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL24596808 | 0.80 | CTSK (0.41) | CTSKCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL12393191 | 0.79 | CTSK (0.44) | CTSKCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL20924692 | 0.76 | CTSK (0.35) | CTSKCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL24596804 | 0.76 | CTSK (0.41) | CTSKCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL12393190 | 0.74 | CTSK (0.46) | CTSKCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL12120311 | 0.74 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL28740123 | 0.74 | SCN1A (0.40) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL28740195 | 0.74 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |
| WO-1998039349-A1 | PROTECTING GROUP FOR SYNTHESIZING OLIGONUCLEOTIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |