Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25884999 | 0.88 | CTSK (0.45) | CTSKALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL24596808 | 0.79 | CTSK (0.41) | CTSKCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12393191 | 0.77 | CTSK (0.44) | CTSKCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25029097 | 0.76 | KDM4E (0.37) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28905852 | 0.76 | CTSK (0.60) | CTSKKMT2A | |
| SCHEMBL8588152 | 0.76 | CTSK (0.39) | CTSKALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL30784696 | 0.75 | CTSK (0.35) | CTSKCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11924542 | 0.75 | CTSK (0.48) | CTSKALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL13162318 | 0.75 | CHRNB2 (0.41) | ALDH1A1TP53PKMKDM4ECHRNB2 | |
| SCHEMBL26700647 | 0.75 | KDM4E (0.33) | ALDH1A1TP53PKMKDM4ECHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147223-A2 | 2'-MODIFIED NUCLEOSIDE BASED OLIGONUCLEOTIDE PRODRUGS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |