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Sugi Predict / Compounds / Trifluoroacetic Acid

Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8588154

CC(O)N(C)C(=O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 4/20 0.44
▸ CHRM4 P08173 4/20 0.44
▸ CHRM5 P08912 4/20 0.44
▸ CHRM1 P11229 4/20 0.44
▸ CHRM3 P20309 4/20 0.44
▸ TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434420 0.93 CHRM2 (0.48) CHRM2CHRM4CHRM5CHRM1CHRM3
Trifluoroacetic Acid SCHEMBL1131909 0.81 TP53 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
Trifluoroacetic Acid SCHEMBL3202273 0.79 TP53 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL21488272 0.77 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Trifluoroacetic Acid SCHEMBL5874606 0.77 TP53 (0.36) TP53
SCHEMBL16000128 0.77 CHRM2 (0.50) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL18334449 0.76 CHRM2 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL16380790 0.76 CHRM2 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
Trifluoroacetic Acid SCHEMBL3140803 0.75 TP53 (0.44) TP53
Trifluoroacetic Acid SCHEMBL27714775 0.75 TP53 (0.44) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998039349-A1 PROTECTING GROUP FOR SYNTHESIZING OLIGONUCLEOTIDE ANALOGS ISIS PHARMACEUTICALS, INC. (US) 1998-09-11 — — WO disclosed