Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588340 | 0.87 | CNR1 (0.35) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29353331 | 0.83 | NPC1 (0.49) | ALDH1A1CYP2C9NPC1RAB9APOLB | |
| SCHEMBL272931 | 0.83 | NPC1 (0.49) | ALDH1A1CYP2C9NPC1RAB9APOLB | |
| SCHEMBL23222483 | 0.82 | LMNA (0.39) | ALDH1A1CYP2C9NPC1RAB9APOLB | |
| Bisoctrizole SCHEMBL29358089 | 0.82 | NPC1 (0.43) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A | |
| Bisoctrizole SCHEMBL30113083 | 0.82 | NPC1 (0.43) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A | |
| Bisoctrizole SCHEMBL5994392 | 0.82 | NPC1 (0.43) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A | |
| Bisoctrizole SCHEMBL39191 | 0.82 | NPC1 (0.43) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A | |
| SCHEMBL5159425 | 0.80 | NPC1 (0.43) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A | |
| SCHEMBL9314160 | 0.79 | NPC1 (0.40) | ALDH1A1CYP3A4CYP2C9ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10251502-A | — | — | None | — | — | JP | disclosed |
| JP-10251503-A | — | — | None | — | — | JP | disclosed |
| JP-H10251502-A | POLYCARBONATE RESIN COMPOSITION | SUMITOMO DOW LTD | 1998-09-22 | — | — | JP | disclosed |
| JP-H10251503-A | POLYCARBONATE RESIN COMPOSITION | SUMITOMO DOW LTD | 1998-09-22 | — | — | JP | disclosed |