Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.57 |
| ▸ | NPY1R | P25929 | 6/20 | 0.57 |
| ▸ | NPY2R | P49146 | 4/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588362 | 1.00 | NPY4R (0.57) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL29398068 | 0.92 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL4543180 | 0.91 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30632623 | 0.91 | NPY4R (0.60) | NPY4RNPY1RNPY2RNPY5RMMP2 | |
| SCHEMBL30680480 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL10943030 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL7645668 | 0.89 | NPY4R (0.61) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7645663 | 0.89 | NPY4R (0.61) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29370105 | 0.89 | NPY4R (0.55) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL29666731 | 0.89 | BACE1 (0.57) | NPY4RNPY1RNPY2RNPY5RBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | claimed |
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |