SCHEMBL6269999

SCHEMBL6269999

OC1(c2ccccc2)C=CC=CC1(O)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.34
OPRM1 P35372 3/20 0.34
OPRK1 P41145 3/20 0.34
TSHR P16473 1/20 0.33
AKR1C1 Q04828 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
POLB P06746 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA9 Q16790 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA14 Q9ULX7 1/20 0.32
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773331 0.71 OPRM1 (0.35) OPRL1OPRM1OPRK1MAOAMAOB
SCHEMBL11749210 0.71 POLB (0.43) OPRL1OPRM1OPRK1TSHRAKR1C1
SCHEMBL10782019 0.70 POLB (0.36) OPRL1OPRM1OPRK1POLBGPR55
SCHEMBL4089733 0.67 HDAC4 (0.36) OPRL1OPRM1OPRK1AKR1C1HDAC1
SCHEMBL27829224 0.67 HDAC1 (0.31) HDAC1HDAC2
SCHEMBL28833868 0.66
SCHEMBL7546042 0.66 P2RX1 (0.32) AKR1C1
SCHEMBL27906055 0.65 MAOB (0.34) OPRL1OPRM1OPRK1MAOAMAOB
SCHEMBL31134789 0.65 OPRM1 (0.37) OPRL1OPRM1OPRK1TSHRAKR1C1
SCHEMBL8080060 0.63 HDAC9 (0.47) OPRL1OPRM1OPRK1TSHRHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114006126-B Lithium-sulfur battery diaphragm material and preparation method thereof 东北师范大学 2023-06-13 CN disclosed
CN-114006126-A Lithium-sulfur battery diaphragm material and preparation method thereof 东北师范大学 2022-02-01 CN disclosed
US-8338339-B2 Supplying biphenyl and polyphenol oxidase THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2012-12-25 US disclosed
WO-2005058062-A2 A PROCESS FOR INHIBITION OF PROTEOLYTIC ACTIVITY DURING THE ENSILING OF FORAGES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-06-30 WO disclosed
US-20050129740-A1 Process for inhibition of proteolytic activity during the ensiling of forages UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE, THE 2005-06-16 US disclosed
US-5340483-A Purification a mixture by enzymatical oxidation a phenolic compound with tyrosinas to a compound which can be adsorbed by chitosan UNIVERSITY OF MARYLAND AT COLLEGE PARK (US) 1994-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129740-A1 Process for inhibition of proteolytic activity during the ensiling of forages PREP, DNPEP, FAP OPRL1 3478/4885OPRM1 4108/4885OPRK1 3534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.