Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193935 | 0.71 | GPR3 (0.37) | ALDH1A1MAPT | |
| SCHEMBL5373174 | 0.71 | KDM4E (0.34) | — | |
| SCHEMBL7288679 | 0.71 | — | — | |
| SCHEMBL9581901 | 0.69 | BCHE (0.35) | CYP3A4MAPT | |
| SCHEMBL4014977 | 0.67 | L3MBTL1 (0.38) | ALDH1A1CYP1A2MAPT | |
| SCHEMBL9581979 | 0.67 | — | — | |
| SCHEMBL10813815 | 0.67 | — | — | |
| SCHEMBL3054238 | 0.67 | EGFR (0.30) | — | |
| SCHEMBL2268788 | 0.67 | SMN1; SMN2 (0.38) | ALDH1A1 | |
| SCHEMBL405536 | 0.67 | TSHR (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483881-B1 | 3-Amidoindolyl derivatives | MERRELL PHARMA INC (US) | 1998-01-21 | — | — | EP | disclosed |
| EP-0483881-A1 | 3-Amidoindolyl derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1992-05-06 | — | — | EP | disclosed |