Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589267 | 1.00 | HSD17B10 (0.39) | HSD17B10PARP1SMN1; SMN2NR1H2ATM | |
| SCHEMBL71903 | 0.86 | NR1H2 (0.45) | HSD17B10SMN1; SMN2NR1H2ATM | |
| SCHEMBL71904 | 0.86 | NR1H2 (0.45) | HSD17B10SMN1; SMN2NR1H2ATM | |
| SCHEMBL283443 | 0.86 | NR1H2 (0.45) | HSD17B10SMN1; SMN2NR1H2ATM | |
| Hydrochloric Acid SCHEMBL5780705 | 0.85 | HSD17B10 (0.37) | HSD17B10PARP1NR1H2 | |
| Hydrochloric Acid SCHEMBL5780709 | 0.85 | HSD17B10 (0.37) | HSD17B10PARP1NR1H2 | |
| SCHEMBL8589268 | 0.79 | PARP1 (0.35) | HSD17B10PARP1SMN1; SMN2ATM | |
| SCHEMBL135177 | 0.77 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2NR1H2ATM | |
| SCHEMBL47049 | 0.77 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2NR1H2ATM | |
| SCHEMBL133363 | 0.77 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2NR1H2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050030-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |