Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 6/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 6/20 | 0.45 |
| ▸ | GRIK4 | Q16099 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287290 | 0.90 | CA12 (0.47) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8687379 | 0.86 | GRIA1 (0.49) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8589859 | 0.85 | PARP1 (0.53) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8589622 | 0.84 | GRIA1 (0.45) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8688995 | 0.83 | GRIK3 (0.56) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8591048 | 0.82 | GRIA2 (0.47) | PARP1GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL8593265 | 0.79 | CA12 (0.48) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8687373 | 0.79 | CA12 (0.48) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8687221 | 0.78 | GRIA2 (0.59) | CA12CA9PARP1GRIK1GRIA1 | |
| SCHEMBL8687475 | 0.77 | GRIK3 (0.51) | CA12CA9PARP1GRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873321-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |