Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687373 | 0.89 | CA12 (0.48) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8688995 | 0.84 | GRIK3 (0.56) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8687475 | 0.84 | GRIK3 (0.51) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8687221 | 0.83 | GRIA2 (0.59) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8687379 | 0.83 | GRIA1 (0.49) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8688421 | 0.82 | GRIA2 (0.47) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8686996 | 0.81 | GRIA2 (0.51) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8687548 | 0.81 | GRIK3 (0.50) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8692369 | 0.81 | GRIK3 (0.48) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL8589503 | 0.79 | CA12 (0.47) | CA12CA9GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873321-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1995035289-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |