Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | TK1 | P04183 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949444 | 0.84 | LMNA (0.46) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL16653120 | 0.81 | TK1 (0.43) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL10950422 | 0.81 | MAPK1 (0.43) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL15538150 | 0.79 | HPGD (0.45) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL6713750 | 0.79 | MAPK1 (0.42) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL27407778 | 0.74 | MAPK1 (0.41) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL1398305 | 0.74 | TK1 (0.39) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL5352507 | 0.74 | MAPK1 (0.38) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL7643586 | 0.72 | MAPK1 (0.51) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL22440022 | 0.71 | LMNA (0.41) | MAPK1HPGDTYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618923-A4 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL. | GLAXO INC (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0618923-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO WELLCOME INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012129-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO INC. (US) | 1993-06-24 | — | — | WO | disclosed |