Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393697 | 0.84 | ENPP2 (0.47) | ENPP2AURKAAURKBALDH1A1CA12 | |
| SCHEMBL28335505 | 0.82 | ENPP2 (0.50) | ENPP2PHLPP2ALDH1A1CA12CA1 | |
| SCHEMBL10825025 | 0.82 | ENPP2 (0.50) | ENPP2PHLPP2ALDH1A1CA12CA1 | |
| SCHEMBL66550 | 0.79 | ENPP2 (0.60) | ENPP2PHLPP2ALDH1A1CTDSP1CA12 | |
| SCHEMBL11290527 | 0.77 | ENPP2 (0.55) | ENPP2PHLPP2ALDH1A1CTDSP1CA12 | |
| SCHEMBL10957199 | 0.77 | CD40 (0.56) | ENPP2ALDH1A1CA12CA1CA2 | |
| SCHEMBL9354138 | 0.77 | ENPP2 (0.47) | ENPP2PHLPP2ALDH1A1CA12CA1 | |
| SCHEMBL5677351 | 0.76 | ENPP2 (0.49) | ENPP2PHLPP2ALDH1A1CA12CA1 | |
| SCHEMBL1755227 | 0.76 | ENPP2 (0.56) | ENPP2PHLPP2ALDH1A1CA12CA1 | |
| SCHEMBL5674967 | 0.76 | AURKA (0.54) | AURKAAURKBALDH1A1CTDSP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555699-B1 | Process for the preparation of aminourethanes | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0555699-A2 | Aromatic compounds substituted by an urethane group and by an amino group | BAYER AG (DE) | 1993-08-18 | — | — | EP | disclosed |
| US-3988310-A | FIBER-REACTIVE DYES; CELLULOSE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |