Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.44 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604369 | 0.88 | TIMP3 (0.49) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL8589578 | 0.84 | ENPP2 (0.46) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL5720575 | 0.82 | POLB (0.43) | TNNI3TNNT2TNNC1HKDC1ALDH1A1 | |
| SCHEMBL9350837 | 0.81 | TIMP3 (0.49) | GAATNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL9723988 | 0.78 | CASP6 (0.48) | GAAALDH1A1TDP1CA1CA2 | |
| SCHEMBL8589696 | 0.77 | ENPP2 (0.49) | ENPP2ALDH1A1LMNACASP6KMT2A | |
| SCHEMBL9765207 | 0.74 | AURKB (0.52) | TNNI3TNNT2TNNC1HKDC1ALDH1A1 | |
| SCHEMBL10422829 | 0.73 | TIMP3 (0.48) | TNNI3TNNT2TNNC1HKDC1ALDH1A1 | |
| SCHEMBL8153748 | 0.73 | ENPP2 (0.48) | ENPP2GAAALDH1A1LMNATDP1 | |
| SCHEMBL9818524 | 0.72 | ENPP2 (0.51) | ENPP2GAAALDH1A1TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0144766-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0159292-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| EP-0125650-B1 | REACTIVE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING AND PRINTING OF SUBSTRATES | BAYER AG (DE) | 1987-04-01 | — | — | EP | disclosed |
| EP-0159292-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0144766-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |
| EP-0139248-A2 | Reactive dyes | BAYER AG (DE) | 1985-05-02 | — | — | EP | disclosed |
| EP-0125650-A2 | Reactive dyes, process for their preparation and their use in the dyeing and printing of substrates | BAYER AG (DE) | 1984-11-21 | — | — | EP | disclosed |
| EP-0063739-B1 | METHOD OF PREPARING COPPER COMPLEXES OF AZO DYESTUFFS | BAYER AG (DE) | 1984-06-27 | — | — | EP | disclosed |
| EP-0013765-B1 | REACTIVE AZODYESTUFFS, THEIR PREPARATION AND THEIR USE FOR DYEING MATERIALS CONTAINING HYDROXYL OR AMIDE GROUPS | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0065479-A2 | Reactive dyestuffs, process for their preparation and their use in dyeing and printing materials containing hydroxyl groups or nitrogen | BAYER AG (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0063739-A1 | Method of preparing copper complexes of azo dyestuffs | BAYER AG (DE) | 1982-11-03 | — | — | EP | disclosed |
| US-4294580-A | HYDROXYL OR NITROGEN, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4255325-A | AZO, ANTHRAQUINONE, FORMAZANE, AND PHTHALOCYANINE DYES; COLOR AND WASHFASTNESS; AMINO HALO TRIAZINE CARBAZIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |
| EP-0019785-A2 | Reactive dyestuffs, their preparation and their use in dyeing and printing cellulose or polypeptides | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| EP-0013765-A1 | Reactive azodyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4079051-A | 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4052386-A | REACTIVE PHTHALOCYANINE DYESTUFFS CONTAINING A FLUOROPYRIMIDINYL GROUP | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |