Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630664 | 0.89 | KDM4C (0.41) | LMNAKMT2AMEN1ALDH1A1KDM4C | |
| SCHEMBL28236062 | 0.85 | SOAT1 (0.39) | PAOXLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL22130340 | 0.83 | KMT2A (0.36) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL2835998 | 0.82 | GABRP (0.36) | LMNAKMT2AMEN1ALDH1A1SLC6A2 | |
| SCHEMBL23646889 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL6557508 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL6557859 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL23646902 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL11398429 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL25834706 | 0.81 | CES2 (0.50) | LMNAKMT2AMEN1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672032-B1 | NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES | ASTRA AB (SE) | 1998-01-07 | — | — | EP | disclosed |
| US-5693630-A | FOR TREATMENT OF PSYCHIATRIC DISORDERS | ASTRA AKTIEBOLAG (SE) | 1997-12-02 | — | — | US | disclosed |
| EP-0672032-A1 | NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES | Astra Aktiebolag (SE) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995009835-A1 | NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES | ASTRA AKTIEBOLAG (SE) | 1995-04-13 | — | — | WO | disclosed |