Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486014 | 0.83 | CA2 (0.51) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL579071 | 0.82 | CA2 (0.47) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL29469809 | 0.78 | CA1 (0.58) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL2227362 | 0.78 | CA1 (0.58) | CA1CA2CA9MAPK1FTO | |
| Hydrochloric Acid SCHEMBL29970142 | 0.76 | CA1 (0.56) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL10414792 | 0.76 | CA2 (0.36) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL7456332 | 0.75 | ALDH1A1 (0.39) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL10690230 | 0.74 | HPGD (0.40) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL10480797 | 0.74 | CA1 (0.58) | CA1CA2CA9MAPK1FTO | |
| SCHEMBL30203439 | 0.74 | CA1 (0.58) | CA1CA2CA9MAPK1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| CN-106459063-A | MERKs-specific pyrimidine compounds | 北卡罗来纳-查佩尔山大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-2432782-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133318-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | CA1 4540/4885CA2 3770/4885CA9 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.