Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 9/20 | 0.80 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.80 |
| ▸ | FPR3 | P25089 | 1/20 | 0.80 |
| ▸ | GPR183 | P32249 | 1/20 | 0.80 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.80 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591222 | 0.89 | NTSR1 (0.72) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL1650932 | 0.89 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL29376784 | 0.89 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9153323 | 0.88 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8590180 | 0.85 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9083930 | 0.85 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8413079 | 0.84 | NTSR1 (0.67) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8297145 | 0.84 | NTSR1 (0.65) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9083148 | 0.84 | NTSR1 (0.67) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9082930 | 0.83 | NTSR1 (0.66) | NTSR1NTSR2FPR3GPR183SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420141-A | Capable of binding to neurotensin receptor | SANOFI (FR) | 1995-05-30 | — | — | US | claimed |
| US-5744491-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5744493-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5635526-A | POSSESSES ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM OR THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1997-06-03 | — | — | US | disclosed |
| US-5616592-A | USEFUL FOR DISORDERS OF CARDIOVASCULAR, GASTROINTESTINAL AND PSYCHOLOGICAL DISORDERS | SANOFI (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5607958-A | NEUROTENSIN RECEPTOR BINDERS | SANOFI (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5420141-A | Capable of binding to neurotensin receptor | SANOFI (FR) | 1995-05-30 | — | — | US | disclosed |