Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | SDHA | P31040 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CALML3 | P27482 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590019 | 0.90 | MAOA (0.55) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL8590924 | 0.87 | MAOA (0.61) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6755402 | 0.86 | MAOA (0.60) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6753194 | 0.85 | MAOA (0.59) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6859879 | 0.85 | MAOB (0.72) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6861537 | 0.85 | MAOB (0.72) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL8591887 | 0.85 | MAOA (0.56) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6755502 | 0.85 | MAOA (0.58) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL6755401 | 0.84 | MAOA (0.53) | F10MAOAMAOBPTGS1SDHA | |
| SCHEMBL13298924 | 0.84 | MAOA (0.61) | F10MAOAMAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673370-B1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0673370-B1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1994013649-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |