Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687991 | 0.85 | KMT2A (0.92) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL29581156 | 0.85 | KMT2A (1.00) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL214075 | 0.85 | KMT2A (1.00) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL3686929 | 0.84 | KMT2A (0.76) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL20476723 | 0.82 | KMT2A (0.73) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL28274299 | 0.82 | KMT2A (0.73) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL11658428 | 0.82 | KMT2A (0.73) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL13475675 | 0.81 | KMT2A (0.71) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL2382803 | 0.81 | KMT2A (0.66) | KMT2AAPPKDM4EALDH1A1HPGD | |
| SCHEMBL10103705 | 0.80 | KMT2A (0.76) | KMT2AAPPKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467559-B | Fused bisindole derivatives and process for producing the same | 苏州大学 | 2020-02-11 | — | — | CN | claimed |
| CN-109503454-B | Preparation method of indole compound | 北京化工大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-109535061-B | 3-nitrosoindole derivative and preparation method thereof | 苏州大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-109467559-B | Fused bisindole derivatives and process for producing the same | 苏州大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-109535061-A | A kind of 3- nitroso-indol derivative and preparation method thereof | 苏州大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-109467559-A | Condensed bisindole derivatives and preparation method thereof | 苏州大学 | 2019-03-15 | — | — | CN | disclosed |
| US-5714496-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHERSCLEROSIS | ZENECA LIMITED (GB) | 1998-02-03 | — | — | US | disclosed |
| EP-0656897-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-01-07 | — | — | EP | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |