SCHEMBL8591995

SCHEMBL8591995

CC[SiH2]C1(c2ccccc2)CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116500 0.81 DPP4 (0.35) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL19580120 0.80 DPP4 (0.33) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL29035084 0.80 DRD3 (0.35) DPP4SLC6A4SLC6A2SLC6A3DRD3
SCHEMBL19580118 0.80 DPP4 (0.33) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL10807455 0.78 DPP4 (0.35) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL5382232 0.78 CRHBP (0.32)
SCHEMBL2356054 0.77 SLC6A4 (0.33) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL6676176 0.74 GRIN2D (0.34) DPP4SLC6A4SLC6A2SLC6A3
SCHEMBL16460539 0.73 SIGMAR1 (0.30)
SCHEMBL28497077 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0491843-A4 ANTIPERSPIRANT 1993-04-14 EP claimed
EP-0491843-A1 ANTIPERSPIRANT. GILLETTE CO (US) 1992-07-01 EP claimed
WO-1991004009-A1 ANTIPERSPIRANT THE GILLETTE COMPANY (US) 1991-04-04 WO claimed
CN-101157770-B Enhanced boron nitride composition and compositions made therewith GEN ELECTRIC 2012-11-14 CN disclosed
WO-1998055431-A1 PROCESS FOR THE CONVERSION OF HYDROCARBONS PHILLIPS PETROLEUM COMPANY (US) 1998-12-10 WO disclosed
EP-0595804-A1 CLEAN CONDITIONING COMPOSITIONS FOR HAIR THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 EP disclosed
EP-0563129-A4 MOLDABLE BODY PAD 1993-11-03 EP disclosed
EP-0563129-A1 MOLDABLE BODY PAD JMK International Inc. (US) 1993-10-06 EP disclosed
EP-0595804-A4 CLEAN CONDITIONING COMPOSITIONS FOR HAIR. PROCTER & GAMBLE (US) 1993-08-12 EP disclosed
WO-1992009250-A1 MOLDABLE BODY PAD JMK INTERNATIONAL, INC. (US) 1992-06-11 WO disclosed
WO-1991016878-A1 CLEAN CONDITIONING COMPOSITIONS FOR HAIR THE PROCTER & GAMBLE COMPANY (US) 1991-11-14 WO disclosed