Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279313 | 0.88 | TSHR (0.54) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL29556511 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL28408395 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL334763 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL27649840 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL547217 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL28958222 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL4078013 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| SCHEMBL10256765 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CTSDHSD17B10TSHRKDM4E | |
| Acetic Acid SCHEMBL28891461 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CTSDTSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830356-A4 | PROCESS FOR THE SYNTHESIS OF BENZO(b)THIOPHENES | LILLY CO ELI (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0830356-A1 | PROCESS FOR THE SYNTHESIS OF BENZO(b)THIOPHENES | ELI LILLY AND COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040678-A1 | PROCESS FOR THE SYNTHESIS OF BENZO[b]THIOPHENES | ELI LILLY AND COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |