SCHEMBL28958222

SCHEMBL28958222

CC(=S)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
CTSD P07339 1/20 0.53
TDP1 Q9NUW8 4/20 0.53
ALPL P05186 2/20 0.53
HSD17B10 Q99714 1/20 0.50
MAPT P10636 5/20 0.49
GAA P10253 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 5/20 0.49
TSHR P16473 1/20 0.49
HPGD P15428 2/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
GPR35 Q9HC97 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8592467 0.83 ALDH1A1 (0.60) ALDH1A1CTSDTDP1HSD17B10MAPT
SCHEMBL397873 0.82 ALDH1A1 (0.58) ALDH1A1CTSDTDP1ALPLMAPT
SCHEMBL28408395 0.82 ALDH1A1 (0.63) ALDH1A1CTSDTDP1ALPLHSD17B10
SCHEMBL29556511 0.82 ALDH1A1 (0.63) ALDH1A1CTSDTDP1ALPLHSD17B10
SCHEMBL334763 0.82 ALDH1A1 (0.63) ALDH1A1CTSDTDP1ALPLHSD17B10
SCHEMBL397874 0.82 ALDH1A1 (0.58) ALDH1A1CTSDTDP1ALPLMAPT
SCHEMBL6142099 0.80 ALDH1A1 (0.56) ALDH1A1CTSDTDP1ALPLMAPT
SCHEMBL547217 0.80 ALDH1A1 (0.56) ALDH1A1CTSDTDP1HSD17B10MAPT
SCHEMBL1206488 0.80 CTSD (0.58) ALDH1A1CTSDTDP1ALPLMAPT
SCHEMBL27649840 0.80 ALDH1A1 (0.56) ALDH1A1CTSDTDP1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed