Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592650 | 0.84 | TDP1 (0.44) | SOD1MAOBTDP1L3MBTL1 | |
| SCHEMBL8591890 | 0.82 | TP53 (0.46) | MAOBALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL8597171 | 0.80 | KDM4E (0.46) | MAOBKDM4EALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL8596853 | 0.79 | DHFR (0.47) | MAOBSMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL8592993 | 0.79 | SOD1 (0.48) | SOD1L3MBTL1NR4A2 | |
| SCHEMBL8592046 | 0.79 | KDM4E (0.45) | BCHEKDM4EALDH1A1SMN1; SMN2CD274 | |
| SCHEMBL7711687 | 0.79 | TP53 (0.46) | MAOBALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL13766428 | 0.78 | SOD1 (0.50) | SOD1BCHEMAOBKDM4EALDH1A1 | |
| SCHEMBL2287384 | 0.78 | SOD1 (0.54) | SOD1BCHEMAOBKDM4EALDH1A1 | |
| SCHEMBL8782035 | 0.78 | HIF1A (0.47) | SOD1MAOBSMN1; SMN2CD274TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |