Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592955 | 1.00 | GAA (0.43) | GAARAB9ALTA4HLMNAMAPT | |
| SCHEMBL8594358 | 0.88 | HIF1A (0.41) | LTA4HMAPTNR5A1PLK1KDM4E | |
| SCHEMBL8594356 | 0.88 | HIF1A (0.41) | LTA4HMAPTNR5A1PLK1KDM4E | |
| SCHEMBL8593363 | 0.88 | FFAR1 (0.44) | MAPT | |
| SCHEMBL8593364 | 0.88 | FFAR1 (0.44) | MAPT | |
| SCHEMBL8593937 | 0.87 | FFAR1 (0.40) | RAB9AMAPTNPC1KDM4EL3MBTL1 | |
| SCHEMBL8593935 | 0.87 | FFAR1 (0.40) | RAB9AMAPTNPC1KDM4EL3MBTL1 | |
| SCHEMBL8595214 | 0.87 | KDM4E (0.41) | RAB9ALMNANPC1KDM4E | |
| SCHEMBL8595212 | 0.87 | KDM4E (0.41) | RAB9ALMNANPC1KDM4E | |
| SCHEMBL8593718 | 0.86 | CAPN1 (0.40) | RAB9ANPC1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |