Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593363 | 1.00 | FFAR1 (0.44) | FFAR1POLBMAPTSMN1; SMN2FFAR4 | |
| SCHEMBL8593935 | 0.90 | FFAR1 (0.40) | FFAR1MAPTFFAR4MAOB | |
| SCHEMBL8593937 | 0.90 | FFAR1 (0.40) | FFAR1MAPTFFAR4MAOB | |
| SCHEMBL8592285 | 0.88 | FFAR1 (0.42) | FFAR1POLBMAPTSMN1; SMN2FFAR4 | |
| SCHEMBL8592284 | 0.88 | FFAR1 (0.42) | FFAR1POLBMAPTSMN1; SMN2FFAR4 | |
| SCHEMBL8592956 | 0.88 | GAA (0.43) | MAPT | |
| SCHEMBL8592955 | 0.88 | GAA (0.43) | MAPT | |
| SCHEMBL8595214 | 0.85 | KDM4E (0.41) | FFAR1SMN1; SMN2FFAR4MAOBSENP8 | |
| SCHEMBL8595212 | 0.85 | KDM4E (0.41) | FFAR1SMN1; SMN2FFAR4MAOBSENP8 | |
| SCHEMBL8593718 | 0.84 | CAPN1 (0.40) | FFAR1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |