Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593937 | 1.00 | FFAR1 (0.40) | FFAR1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8593363 | 0.90 | FFAR1 (0.44) | FFAR1MAPTFFAR4MAOB | |
| SCHEMBL8593364 | 0.90 | FFAR1 (0.44) | FFAR1MAPTFFAR4MAOB | |
| SCHEMBL8593729 | 0.88 | HIF1A (0.42) | FFAR1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8593728 | 0.88 | HIF1A (0.42) | FFAR1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8592955 | 0.87 | GAA (0.43) | MAPTKDM4ENPC1RAB9ATDP1 | |
| SCHEMBL8592956 | 0.87 | GAA (0.43) | MAPTKDM4ENPC1RAB9ATDP1 | |
| SCHEMBL8595214 | 0.87 | KDM4E (0.41) | FFAR1OPRL1FFAR4KDM4EMAOB | |
| SCHEMBL8595212 | 0.87 | KDM4E (0.41) | FFAR1OPRL1FFAR4KDM4EMAOB | |
| SCHEMBL8592954 | 0.86 | HIF1A (0.43) | KDM4EMAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |