Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590737 | 0.87 | NPC1 (0.41) | POLBRAB9AMAOBNPC1MAPT | |
| SCHEMBL8593358 | 0.87 | CD274 (0.36) | POLBTP53APPNR4A2F2 | |
| SCHEMBL8592993 | 0.84 | SOD1 (0.48) | POLBLMNARAB9ANR4A2L3MBTL1 | |
| SCHEMBL8592217 | 0.83 | FFAR1 (0.45) | LMNARAB9ASMN1; SMN2F2PRSS1 | |
| SCHEMBL8597171 | 0.82 | KDM4E (0.46) | APPRAB9ANR4A2SMN1; SMN2F2 | |
| SCHEMBL8590712 | 0.80 | LTA4H (0.49) | RAB9AATML3MBTL1SMN1; SMN2F2 | |
| SCHEMBL8592650 | 0.80 | TDP1 (0.44) | RAB9AL3MBTL1RXRARXRBF2 | |
| SCHEMBL8597491 | 0.80 | FFAR1 (0.45) | POLBAPPRAB9ANR4A2L3MBTL1 | |
| SCHEMBL8593753 | 0.80 | FFAR1 (0.45) | APPLMNARAB9ARXRARXRB | |
| SCHEMBL8594460 | 0.79 | MRGPRX4 (0.35) | LMNARAB9AL3MBTL1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |