SCHEMBL85946

SCHEMBL85946

COc1cc(N)c(C(=O)O)cc1OC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.69
LCK P06239 1/20 0.60
FYN P06241 1/20 0.60
ALDH1A1 P00352 4/20 0.56
MYC P01106 1/20 0.50
GAA P10253 2/20 0.47
HPGD P15428 3/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
HTT P42858 1/20 0.47
IDO1 P14902 1/20 0.47
CYP3A4 P08684 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
TPMT P51580 1/20 0.47
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5012089 0.98 KDM4E (0.67) KDM4ELCKFYNALDH1A1MYC
Nitrogen SCHEMBL28644623 0.96 KDM4E (0.65) KDM4ELCKFYNALDH1A1MYC
SCHEMBL19426394 0.91 KDM4E (0.64) KDM4ELCKFYNALDH1A1MYC
SCHEMBL2890743 0.90 ALDH1A1 (0.59) KDM4ELCKFYNALDH1A1MYC
SCHEMBL18669213 0.90 KDM4E (0.56) KDM4ELCKFYNALDH1A1MYC
SCHEMBL13671488 0.89 KDM4E (0.57) KDM4ELCKFYNALDH1A1MYC
SCHEMBL2235600 0.88 KDM4E (0.56) KDM4ELCKFYNALDH1A1MYC
SCHEMBL19554291 0.87 KDM4E (0.54) KDM4ELCKFYNALDH1A1MYC
SCHEMBL20746184 0.87 KDM4E (0.54) KDM4ELCKFYNALDH1A1MYC
SCHEMBL14907061 0.87 KDM4E (0.54) KDM4ELCKFYNALDH1A1MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1014 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117965068-B Preparation method and application of waterproof and anticorrosive paint with high bonding strength 惠州市德泰士达科技有限公司 2024-07-12 CN claimed
CN-117965068-A Preparation method and application of waterproof and anticorrosive paint with high bonding strength 惠州市德泰士达科技有限公司 2024-05-03 CN claimed
CN-116854674-A Preparation method of terazosin hydrochloride and intermediate thereof 迪嘉药业集团股份有限公司 2023-10-10 CN claimed
CN-115010671-B One-step synthesis method of 2-substituted quinazolinone 江苏大学 2023-10-10 CN claimed
CN-114409636-B Quinazolinone compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 沈阳药科大学 2023-04-18 CN claimed
CN-115010671-A One-step synthesis method of 2-substituted quinazolinone 江苏大学 2022-09-06 CN claimed
CN-110894189-B Preparation method of erlotinib hydrochloride 山东罗欣药业集团股份有限公司 2021-07-06 CN claimed
CN-110894189-A Preparation method of erlotinib hydrochloride 山东罗欣药业集团股份有限公司 2020-03-20 CN claimed
CN-107245072-A A kind of preparation method of the triazole compound of Tarceva 1,2,3 河南师范大学 2017-10-13 CN claimed
CN-106632271-A Erlotinib derivative with antitumor activity, and preparation method and application thereof 河南师范大学 2017-05-10 CN claimed
WO-2008130924-A2 ISOTOPICALLY-LABELED GLYCANS MOMENTA PHARMACEUTICALS, INC. (US) 2008-10-30 WO claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-1165064-B1 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) HOPE CITY (US) 2004-02-25 EP claimed
US-6337350-B1 CROSSLINKING INHIBITION OF PROTEINS CITY OF HOPE 2002-01-08 US claimed
EP-1165064-A2 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) City of Hope (US) 2002-01-02 EP claimed
WO-2000059875-A2 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) CITY OF HOPE (US) 2000-10-12 WO claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed